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Aplaviroc

Alternative Names: aplaviroc, gw-873140, gw 873140, gw873140
Latest Update: 2018-11-02
Latest Update Note: Clinical Trial Update

Product Description

Aplaviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against HIV-1. Aplaviroc inhibits HIV-1 entry via CCR5 coreceptor interaction. (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Aplaviroc)

Mechanisms of Action: CCR5 Antagonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Aplaviroc

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: HIV Infections|Acquired Immunodeficiency Syndrome

Phase 2: HIV Infections|Communicable Diseases|Acquired Immunodeficiency Syndrome|Deficiency Diseases

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
2005-001246-16

P3

Completed

HIV Infections

2008-02-29

CCR104456

P3

Terminated

HIV Infections

2007-10-01

CCR102709

P3

Terminated

HIV Infections|Acquired Immunodeficiency Syndrome

2007-09-11

NCT00102778

P2

Terminated

Communicable Diseases|HIV Infections|Deficiency Diseases|Acquired Immunodeficiency Syndrome

2007-09-01

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