Product Description
Lisinopril is used alone or together with other medicines to treat high blood pressure (hypertension).Lisinopril works by blocking a substance in the body that causes the blood vessels to tighten. As a result, lisinopril relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. (Sourced from: https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/side-effects/drg-20069129?p=1)
Mechanisms of Action: ACE Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Indonesia | Ireland | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Heart Failure | Heart Failure, Acute | Myocardial Infarction | Hypertension
Known Adverse Events: Heart Failure | Heart Failure, Acute | Myocardial Infarction | Hypertension | Hypotension | Acute Pain | Chest Pain | Dizziness | Headache | Pain Unspecified
Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, China, Nigeria
Active Clinical Trial Count: 4
Highest Development Phases
Phase 3: Hypertension|Kidney Diseases
Phase 2: Acquired Immunodeficiency Syndrome|Albuminuria|Deficiency Diseases|HIV Infections
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| Vanderbilt_University MC | P2 |
Suspended |
Albuminuria|Deficiency Diseases|Kidney Diseases|Acquired Immunodeficiency Syndrome|HIV Infections |
2025-02-01 |
|
| FAN | P3 |
Not yet recruiting |
Kidney Diseases |
None |
|
| CTR20213088 | P3 |
Not yet recruiting |
Hypertension |
None |
|
| CTR20213095 | P3 |
Not yet recruiting |
Hypertension |
None |