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Lestaurtinib

Alternative Names: lestaurtinib, cep-701
Latest Update: 2024-07-15
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: PK Inhibitor,TK Inhibitor,JAK2 Inhibitor,FLT3 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral,Topical

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Teva
Company Location: PETACH TIKVA L3 49131
Company CEO: Kåre Schultz
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Lestaurtinib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: T-Cell Leukemia|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma|Acute Lymphoid Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma

Phase 2: Myelofibrosis|Acute Myeloid Leukemia|Thrombocytosis|Thrombocythemia, Essential|Multiple Myeloma|Psoriasis|Polycythemia Vera|Prostate Cancer|Leukemia|Oncology Hematological Unspecified

Phase 1: Neuroblastoma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
2006-7041-83/hah

N/A

Not yet recruiting

Multiple Sclerosis

2018-07-01

AALL0631

P3

Completed

Acute Lymphoid Leukemia|T-Cell Leukemia|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

2017-09-30

GCO 07-0548-00104

P2

Unknown status

Polycythemia Vera|Thrombocytosis|Thrombocythemia, Essential|Myelofibrosis

2013-09-01

CS-2007-20040

P2

Completed

Myelofibrosis|Leukemia

2010-05-01

Recent News Events

Date

Type

Title

05/11/2024

PubMed

 A novel anoikis-related signature predicts prognosis risk and treatment responsiveness in diffuse large B-cell lymphoma.

04/01/2024

PubMed

 Identifying the predictive role and the related drugs of oxidative stress genes in the hepatocellular carcinoma.

03/14/2024

PubMed

 Inference of drug off-target effects on cellular signaling using interactome-based deep learning.

02/02/2021

News Article

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