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Anagrelide

Alternative Names: anagrelide, agrylin
Latest Update: 2024-10-29
Latest Update Note: Clinical Trial Update

Product Description

Anagrelide is used to decrease the number of platelets (a type of blood cell that is needed to control bleeding) in the blood of patients who have a bone marrow disorder, in which the body makes too many of one or more types of blood cells, such as essential thrombocythemia (condition in which the body makes too many platelets) or polycythemia vera (condition in which the body makes too many red blood cells and sometimes too many platelets). Anagrelide is in a class of medications called platelet-reducing agents. It works by slowing the production of platelets in the body. (Sourced from: https://medlineplus.gov/druginfo/meds/a601020.html)

Mechanisms of Action: PLA2 Inhibitor,PDE3 Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Argentina | Australia | Austria | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | Croatia | Cyprus | Czech | Denmark | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | Indonesia | Ireland | Israel | Italy | Japan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Netherlands | New Zealand | Norway | Pakistan | Philippines | Poland | Portugal | Romania | Russia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sweden | Switzerland | Taiwan | Thailand | Turkey | Ukraine | United Kingdom | United States

Approved Indications: Thrombosis | Oncology Unspecified

Known Adverse Events: Tachycardia | Abdominal Pain | Back Pain | Chest Pain | Dizziness | Headache | Pain Unspecified | Paresthesia | Pruritus | Dyspnea | Anorexia | Asthenia | Diarrhea | Dyspepsia | Edema | Flatulence

Company: Takeda
Company Location: TOKYO M0 103-8668
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Anagrelide

Countries in Clinic: Canada, China, Hong Kong, Japan, Korea, Singapore, Taiwan, United States

Active Clinical Trial Count: 3

Highest Development Phases

Phase 3: Thrombocythemia, Essential|Thrombocytosis

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

SURPASS ET

P3

Active, not recruiting

Thrombocytosis|Thrombocythemia, Essential

2024-11-30

64%

JapicCTI-205314

P3

Planned

Thrombocythemia, Essential

2022-06-30

jRCT2080225218

P3

Recruiting

Thrombocythemia, Essential

None

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