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Dichloroacetate

Alternative Names: dichloroacetate, dca
Latest Update: 2024-08-23
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: PDK Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Colombia | India | Peru | Taiwan | United Kingdom

Approved Indications: None

Known Adverse Events: None

Company: University of Florida
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Dichloroacetate

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 4: Insulin Resistance

Phase 3: Acidosis, Lactic|Pyruvate Dehydrogenase Complex Deficiency Disease

Phase 2: Healthy Volunteers|Glioblastoma|Head and Neck Cancer|Squamous Cell Carcinoma|Multiple Myeloma|Non-Small-Cell Lung Cancer|Glioma|Breast Cancer|Acidosis, Lactic|MELAS Syndrome

Phase 1: MELAS Syndrome|Liver Cancer|Brain Cancer|Evans Syndrome|Acidosis, Lactic|Glioblastoma|Potassium Deficiency|Lung Cancer|Brain Death|Tumor Lysis Syndrome|Protein Deficiency|Breast Cancer|Head and Neck Cancer|Familial Primary Pulmonary Hypertension|Hypertension, Pulmonary|Pyruvate Dehydrogenase Complex Deficiency Disease|Deficiency Diseases|Brain Injuries|Mitochondrial Diseases|Hyperglycemia|Type 1 Diabetes|Hypoglycemia|Healthy Volunteers

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

DCA

P2

Not yet recruiting

Glioblastoma

2026-12-30

NCT05317455

P1

Not yet recruiting

Type 1 Diabetes|Hypoglycemia

2025-10-01

Application of a new portable ultrasonic diagnostic instrument

N/A

Recruiting

Other

2025-07-31

ACTRN12623001164684

N/A

Not yet recruiting

Nose Cancer

2025-06-30

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