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Hymecromone

Alternative Names: hymecromone, 4-methylumbelliferone
Latest Update: 2025-03-05
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: Hyaluronic Acid Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Bosnia | Bulgaria | China | Czech | France | Lithuania | Morocco | Pakistan | Poland | Russia | Saudi Arabia | Serbia | Slovakia | Slovenia | Taiwan | Turkey | Ukraine

Approved Indications: None

Known Adverse Events: None

Company: Aparna Goel
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Hepatitis A|Lung Diseases, Interstitial|Idiopathic Pulmonary Fibrosis|Hepatitis C, Chronic|Hepatitis B, Chronic|Cholangitis, Sclerosing|Hypertension, Pulmonary

Phase 1: Healthy Volunteers

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
The SOLIS Study

P2

Recruiting

Lung Diseases, Interstitial|Idiopathic Pulmonary Fibrosis

2027-12-31

HAAPS

P2

Recruiting

Cholangitis, Sclerosing

2025-05-01

SATURN

P2

Completed

Hypertension, Pulmonary|Lung Diseases, Interstitial

2023-09-21

QJXDS-22-01

N/A

Unknown status

COVID-19

2022-08-15

Recent News Events

Date

Type

Title

05/08/2024

PubMed

 Rutinosides-derived from Sarocladium strictum 6-O-α-rhamnosyl-β-glucosidase show enhanced anti-tumoral activity in pancreatic cancer cells.

04/28/2024

PubMed

 Biomimetic immobilization of alpha-glucosidase inspired by antibody-antigen specific recognition for catalytic preparation of 4-methylumbelliferone.

01/01/2024

PubMed

 Teaching an Old Drug a New Trick: Targeting Treatment Resistance in Genitourinary Cancers.

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