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Abacavir

Alternative Names: abacavir, ziagen, epzicom, prurisol, km-133, abacavir sulfate, triumeq, trizivir, triumeq pd
Latest Update: 2024-06-25
Latest Update Note: Clinical Trial Update

Product Description

Abacavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Abacavir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although abacavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting (spreading) the HIV virus to other people. (Sourced from: https://medlineplus.gov/druginfo/meds/a699012.html)

Mechanisms of Action: NRT Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: HIV Infections | HIV Infections | HIV Infections | HIV Infections

Known Adverse Events: Headache Disorders | Headache | Chills | Migraine Disorders | Depressive Disorder | Dizziness | Insomnia | Vertigo | Drug Hypersensitivity | Diarrhea | HIV Infections

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Abacavir

Countries in Clinic: Australia, Botswana, Canada, South Africa, Thailand, United States

Active Clinical Trial Count: 8

Highest Development Phases

Phase 3: HIV Infections

Phase 1: Glioma|Kidney Diseases

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

STARLITE

P1

Not yet recruiting

Glioma

2028-05-31

D3

P3

Active, not recruiting

HIV Infections

2026-04-03

DOBINeuro

P3

Active, not recruiting

HIV Infections

2023-02-24

2006-7041-83/hah

P1

Not yet recruiting

Kidney Diseases

2022-02-28

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