Product Description
Abacavir is used along with other medications to treat human immunodeficiency virus (HIV) infection. Abacavir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although abacavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting (spreading) the HIV virus to other people. (Sourced from: https://medlineplus.gov/druginfo/meds/a699012.html)
Mechanisms of Action: NRT Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: HIV Infections | HIV Infections | HIV Infections | HIV Infections
Known Adverse Events: Headache Disorders | Headache | Chills | Migraine Disorders | Depressive Disorder | Dizziness | Insomnia | Vertigo | Drug Hypersensitivity | Diarrhea | HIV Infections
Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, Botswana, Canada, South Africa, Thailand, United States
Active Clinical Trial Count: 8
Highest Development Phases
Phase 3: HIV Infections
Phase 1: Glioma|Kidney Diseases
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| STARLITE | P1 |
Not yet recruiting |
Glioma |
2028-05-31 |
|
| D3 | P3 |
Active, not recruiting |
HIV Infections |
2026-04-03 |
|
| DOBINeuro | P3 |
Active, not recruiting |
HIV Infections |
2023-02-24 |
|
| 2006-7041-83/hah | P1 |
Not yet recruiting |
Kidney Diseases |
2022-02-28 |